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The Division of Nutrition
and Harvard Clinical Nutrition Research Center
HARVARD MEDICAL SCHOOL

Department of Nutrition
HARVARD SCHOOL OF PUBLIC HEALTH

Presents
The 8th Annual Postgraduate Nutrition Symposium

Metabolic Syndrome and Onset of Cancer

March 15 - 16, 2006

Daniel Tosteson Medical Education Center
Carl Walter Amphitheater (2nd Floor)
Harvard Medical School
260 Longwood Avenue
Boston, MA

Chairs: Dr. George Blackburn, MD, PhD;
Dr. W. Allan Walker, MD; and Dr. Jin-Rong Zhou, PhD.

PROGRAM

Wednesday, March 15, 2006
7:30 AM Registration & Continental Breakfast
8:00 Welcome W. Allan Walker, M.D.
Conrad Taff Professor of Nutrition; Director, Division of Nutrition, Harvard Medical School
8:05 Introductory remarks George Blackburn, M.D., Ph.D.
S. Daniel Abraham Associate Professor of Nutrition; Associate Director, Division of Nutrition, Harvard Medical School
SESSION I: METABOLIC SYNDROME (MS) AND CANCER RISK: EPIDEMIOLOGICAL INVESTIGATION
Moderator: John Milner, Ph.D.
Chief of the Nutrition Science Research Group in the Division of Cancer Prevention at the National Cancer Institute
8:10 Epidemiological Evidence on MS and Cancer Development: An Overview of Epidemiological Evidence and Proposed Mechanics Eugenia E. Calle, Ph.D.
American Cancer Society
8:55 The Role of IGF-I Signaling in Cancer Risk and Progression: A Connection Between MS and Cancer Risk Michael N. Pollak, M.D., FRCP
McGill University
9:20 Diabetes, MS and Risk of Breast Cancer Karin Michels, Sc.D., Ph.D.,
Brigham and Women's Hospital,
Harvard Medical School
9:50 Break
10:05 MS, Obesity and Risk of Colon Cancer Edward L. Giovannucci, D.Sc., M.D.,
Harvard School of Public Health
10:30 MS, Obesity and Risk of Prostate Cancer Ann Hsing, Ph.D.,
National Cancer Institute
10:55 Panel Discussion
11:30 Lunch
SESSION II:
BASIC RESEARCH
Moderator: Jin-Rong Zhou, PhD, Assistant Professor of Surgery, Harvard Medical School; Director, Nutrition/Metabolism Lab, Beth Israel Deaconess Medical Center
1:00 PI3K-Akt: A Central Pathway in Both Turmorigenesis and Insulin Signaling Lewis C. Cantley, Ph.D.,
Beth Israel Deaconess Medical Center,
Harvard Medical School
1:15 The Role of Adiponectin in Cancer Development and Progression Christos S. Mantzoros, M.D.,
Beth Israel Deaconess Medical Center,
Harvard Medical School
1:40 Free Fatty Acids, Insulin Resistance and Cancer Richard N. Bergman, Ph.D.,
University of Southern California School of Medicine
2:05 The Role of AMPK in MS and Cancer Neil B. Ruderman, M.D.,
Boston University Medical Center
2:30 The Potential Role of MS in Epigenetic Modulation of Carcinogenesis Sharon A. Ross, Ph.D., M.P.H.,
National Cancer Institute
2:55 The Role of Stress and Inflammatory Pathways in Metabolic Homeostasis and Survival Gokhan Hotamisligil, M.D., Ph.D.,
Harvard School of Public Health
3:25 Panel Discussion
4:15 PM Adjourn for the day


Thursday, March 16
7:30 AM Registration and Continental Breakfast
SESSION III:
PREVENTION AND INTERVENTION: Preclinical and Clinical Studies
Moderator: George L. Blackburn, M.D, Ph.D., S. Daniel Abraham Associate Professor of Nutrition; Associate Director, Division of Nutrition, Harvard Medical School
8:00 Dietary Fat Reduction and Breast Cancer Outcome: Results from the Women's Intervention Nutrition Study (WINS) George L. Blackburn, M.D, Ph.D..
Harvard Medical School
Division of Nutrition
8:30 Dietary and Nutritional Combinations and Cancer Prevention: Targeting MS Jin-Rong Zhou, Ph.D.
9:00 Insulin Sensitizers and Cancer Prevention and Treatment: PPAR-gamma Agonists Bruce Spiegelman, Ph.D.,
Harvard Medical School,
Dana Farber Cancer Institute
9:30 Prostate Cancer Prevention by Nutritional Means to Alleviate MS R. James Barnard, Ph.D.,
UCLA
10:00 Panel Discussion
10:30 Break
SESSION IV: TRANSLATIONAL AND CLINICAL SCIENCE

10:50 WHI Summary and Dietary Implications

John Milner, Ph.D.,
National Cancer Institute

11:00 Panel Discussion
12:00 Closing Remarks Dr. Walker and Dr. Blackburn
Symposium Adjourns

Although there is no fee for the symposium, lunch and refreshments, registration is required. A limited number of discounted rooms ($139) at the adjoining Best Western Inn at Longwood Medical Center, 342 Longwood Ave., Boston MA, 02115 may be reserved by calling (617) 731-4700. In order to receive that rate let them know you are attending Harvard Medical School’s "Metabolic Syndrome" Symposium

Click HERE for an Introduction to this event.


The 2005 Symposium:
The Childhood Obesity Epidemic
Click HERE for program and Webcast links

The 2004 Symposium:
Science-Based Solutions to Obesity:
What is the Role of Academia, Government,
and Industry?

Click HERE for program and Webcast links
Click HERE to go directly to the Webcast site.

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Updated 11/20/2006